Student Research Projects and Theses
Students majoring in Biology have the opportunity to conduct research with our faculty. For students who qualify, 这项研究通常以一个高级论文项目告终,这是学生以生物学荣誉毕业的要求.
Meet our Current Thesis Students
Tyler Allcroft, ’23
在我的毕业论文中,我正在进行Dictyostelium disideum对Rose Bengal和蓝光产生的单线态氧的氧化应激反应的单细胞实验. 我项目的目标是确定细胞周期在我们系统中应激反应的异质性中的作用.
我从事这项研究是因为我对氧化应激如何影响生物系统感兴趣,因为它对癌症和其他疾病有影响. I am interested in oncologic medicine and will apply to medical school this spring.
Alyce Segal, ’23
我的荣誉论文题目是“测试不同大小石蝇(Acroneuria abnormis)对猎物群落的消耗和非消耗效应”. Predators affect prey communities through two pathways – by eating prey (i.e., consumptive effects) and by modifying prey traits (i.e., non-consumptive effects), such as behavior. Predator body size could influence both consumptive and non-consumptive effects, but these effects have rarely been compared across predator sizes. 我的研究使用了野外实验来操纵石蝇(Acroneuria abnormis)的大小和它们捕食猎物的能力(通过口器粘接),并测量了对坦克霍森河(Vernon)水生昆虫猎物群落的影响, CT).
I got into this work as I wanted to be more involved in the field of ecology. Knowing that the state of our planet is less than ideal, 我希望我参与的研究能以这样或那样的方式为一个更健康的星球做出贡献.
Flynn Gorman, ’23
我的荣誉论文关注的是动物个性的后果以及它与摄食率的关系, activity level, 以及无脊椎蜻蜓若虫个体的体型变化. Toscano.
I have been working in Dr. 自2021年5月以来,托斯卡诺的实验室,在这样做的过程中,我得到了一个惊人的机会,在课程之外进一步我的研究经验,同时也有自由设计我自己的实验, collaborate with my lab mates, and gain experience in writing and preparing my own thesis. Additionally, 在博彩平台网址大全的研究使我有资格申请并获得美国国家科学基金会REU项目的研究奖学金,我在俄勒冈大学研究了热液喷口腹足动物的生殖超微结构. 我希望在5月份毕业后继续研究,并将我在博彩平台网址大全学到的技能应用到我的职业生涯中新的、多样化的科学学科中!
Julian Marlowe, ’23
正常的发育取决于一系列复杂的细胞信号系统的一致作用. Notch信号系统与神经发生等重要发育过程有关, wing formation, and the establishment of embryonic polarity. Notch is a membrane-bound receptor that mediates signaling in a juxtracrine fashion, binding to adjacent membrane-bound ligands. In my research, 我正在研究Abruptex等位基因显示的Notch过度激活背后的分子机制.
在大三的时候,我学了很多关于细胞信号和遗传学的课程,开始从事研究工作. 这些课程是非常形成的,激发了我对基因技术的兴趣,这些技术可以用来解剖复杂的途径.
Jacob Borgida, ’23
My research focuses on lysosomal storage diseases, and how gene-targeted therapies are changing what is treatable. 我正在进行图书馆研究和数据库搜索,研究溶酶体贮积病的生物学, newborn screening, 以及针对三种选定疾病的基因靶向治疗,这些疾病可以通过基因测序可靠地检测出来. The three diseases I am focusing on are Krabbe, Gaucher, and Fabry disease. 及早发现每种疾病的致病变异,可以改善健康结果,缩短诊断过程.
During the summer of 2020, 我通过明尼苏达大学医学院的一个实验室进行了神经系统修复基因靶向疗法的研究. After completing a genetics course at Trinity in the spring of 2021, I began research at a clinical genetics lab in Boston named Genomes2People. One of their main projects I contributed to was examining the behavioral, economic, and medical impact of genetic sequencing in newborns. Through this research, 我对遗传学的兴趣激增,我找到了一组疾病,使我能够将我对遗传学的兴趣与细胞生物学结合起来. I plan to pursue medical school after graduating from Trinity in the spring of 2023.
Olivia Pomerleau, ’23
My name is Olivia Pomerleau and I am a thesis student in the biology department. 我目前正在研究皮肤微生物组与特应性皮炎之间的关系, also known as eczema. 更具体地说,我正在研究成人发病的特应性皮炎的治疗方案. 我假设成人发病的特应性皮炎更多的是微生物群失调问题.
我之所以选择这个研究领域,是因为我的阿姨最近被诊断出患有湿疹,而她小时候从未患过湿疹. I also am interested in going to medical school and hopefully pursuing dermatology. 结合我对微生物学的兴趣,我找到了一个完美的研究课题. Currently I am also an EMT at Trinity Health of New England. I have found that emergency medicine is quite different from studying skin diseases.
Henry Lagasse, ’23
而通过观察分子数据来形成系统发育是确定物种如何相互关联的最具体的方法, 形态学资料可以为物种划分和功能性状的进化提供证据. As a result, 在鉴定一个物种时,能够结合分子和形态证据是很重要的.
在我的研究中,我正在研究孢子的会阴形态作为一种可能的新特征,用于鉴定蕨类属内的物种, Polystichum. 蕨类孢子有一个叫做外孢子的外层,外孢子有不同的装饰结构,如脊和穿孔,这些结构在种间是不同的. 我正在使用SEM(扫描电子显微镜)图像对会阴特征进行评分,并将这些特征映射到Polystichum的分子系统发育上,以重建进化史.
我之所以从事这项研究,是因为我对植物生物学很感兴趣,这是我通过学习《博彩平台网址大全》(BIOL 218)获得的。, Botany (BIOL 215), and Evolution of plant structures (BIOL 223). Professor Patel is my thesis advisor for this project.